Saturday, October 18, 2008

Exercise Proven Treatment for Fatty Liver in Diabetics

I found this article and thought it would be of interest to the Cushing's community, since so many suffer from fatty liver and diabetes. My new diet is in response to the way I've been feeling lately, as well as the 225 blood sugar reading I got 2 hours after dinner one day last week. I'm not diagnosed diabetic, but it runs rampant on my maternal side of the family. I figure I need to try to head it off at the pass.


Weekly bouts of moderate aerobic exercise on a bike or treadmill, or a brisk walk, combined with some weightlifting, may cut down levels of fat in the liver by up to 40 percent in people with type 2 diabetes, a study by physical fitness experts at Johns Hopkins shows.

According to researchers, who present their findings on September 18, 2008 at the annual meeting of the American Association of Cardiovascular and Pulmonary Rehabilitation, high liver fat levels are common among people with type 2 diabetes and contribute to heart disease risk.

The NIH-funded study’s lead investigator, exercise physiologist Kerry Stewart, Ed.D., says the rise in the number of people with nonalcoholic fatty liver, mostly due to obesity, signals “a dark trend” because the disease, also called hepatic steatosis, may lead to cirrhosis and subsequent liver failure and transplantation, even cancer, as well as increased risk of diabetes-related heart disease.

“People with type 2 diabetes have added reason to be active and to exercise, not just because it is good for their overall health, but also because our study results pinpoint a key benefit to trimming the fatty liver that complicates their illness and which could accelerate heart disease and liver failure,” says Stewart, a professor of medicine and director of clinical and research exercise physiology at the Johns Hopkins University School of Medicine and its Heart and Vascular Institute.

A majority of the quarter-million people who die each year from all kinds of diabetes do so as a result of some form of heart disease or stroke. And excess body fat is known to increase the likelihood of potentially life-threatening illness because the fat leads to more inflammation in the artery walls, high blood pressure and elevated blood cholesterol levels.

Stewart says the team’s study is believed to be the first to specifically demonstrate the beneficial role played by exercise in controlling hepatic fat levels in people with diabetes.

In the study, 77 diabetic men and women in Baltimore, Md., were divided into two groups.

For a six-month period, half of the study participants were put through a moderate program of sustained aerobic exercise consisting of 45-minute sessions three times a week. They could bicycle, run on a treadmill or take brisk walks. In addition, they lifted stacked weights for about 20 minutes, also three times a week, and not at a heavy-duty pace. The other half of the participants were asked to avoid any formal aerobic fitness or gym classes.

Special magnetic resonance imaging scans performed at the start and end of the study showed much lower levels of liver fat in the active group, while levels remained the same in the nonexercising group (at 5.6 percent and 8.5 percent, respectively). Physical fitness exams were also done.

Among the team’s other findings were better measures in general fitness and fatness among exercisers when compared to the nonexercising group. Averages for peak oxygen uptake levels during treadmill testing, or V02 levels, were greater by 13 percent (25.1 milliliters per kilogram per minute, compared to 22.2 milliliters per kilogram per minute), muscles were stronger by 7 percent (lifting 216.7 pounds, as opposed to 202.8 pounds for seven exercises tested), while percentages of body fat and body weight were each lower by 6 percent (35.5 percent versus 33.2 percent, and 98.5 pounds versus 92.2 pounds, respectively). Even waistlines shrunk on average by 2 inches (39 inches, compared to 41 inches).

“The benefits in improved fitness and fatness are clear, and physicians should really have all people with type 2 diabetes actively engaged in an exercise program,” says Stewart, who plans to further promote moderate exercise through direct talks with referring physicians and through his monthly health blog to the public while he amasses more evidence about the benefits of exercise in people with the disease. An estimated 14 million Americans have been diagnosed with this most common form of diabetes, in which the body cannot use its own life-sustaining insulin and eventually stops producing it.

Stewart says his team’s next steps are to analyze the long-term effect of moderate exercise on diabetes and heart disease, including any improvements in heart and blood vessel structure and function, insulin resistance and arterial inflammation.

The Hopkins study’s exercise program followed current physical fitness guidelines from the American College of Sports Medicine. Their latest research follows another study published in 2005 by the Johns Hopkins scientists, which showed that moderate exercise reduced by more than 20 percent the number of people who develop metabolic syndrome, a clustering of three or more risk factors for developing heart disease, diabetes and stroke. Risk factors include high blood pressure, elevated blood glucose levels, excess abdominal fat and abnormal cholesterol (Newswise).

Time for a Change - In My Diet

I've been away for awhile again. I lost my internet connection for 2 weeks and that was interesting - I lived through it with very little withdrawal, which was a surprise for me. But I did miss all my online friends. I'm on my 4th or 5th data card. Everytime Windows does a service pack, my connection bites the dust.

I'm struggling lately with weight loss. At first, right after my pituitary surgery, the weight came off quickly and easily. So of course there are questions. Am I really cured, or in remission from Cushing's, or whatever you want to call it? Who knows? I just can't sit around and worry about it, and I also can't actively test and investigate since my husband and I both lost our long-time jobs and good health insurance. We now have very expensive insurance that doesn't cover squat on pre-existing conditions for 6 months, and then there's a rather high deductible. So I'm sort of stuck for now and am not going to dwell on it as long as my life is half-way normal. And it is.
For now, anyway!

So my immediate plan is to stay on a low carb diet and see if that helps get the weight loss going again. If it doesn't, it will indicate that I'm dealing with another endocrine issue, whether pituitary or thyroid or whatever. So look for low carb blogs in my bloglist. Tonight I have added
so check it out. There's a lot of good information there.

So I've been low carbing for about 5 or 6 days now and have seen some changes. I lost 2 pounds in the first couple of days. But the biggest change that I've seen so far is that my stomach isn't upset all the time. It's early on in the diet, though, so I will keep you posted